Low Endolymph Calcium Concentrations in deafwaddler2J Mice Suggest that PMCA2 Contributes to Endolymph Calcium Maintenance
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منابع مشابه
The Viscosity of the Pike's Endolymph
The mechanical sensitivity of the semicircular canals of the vertebrates is determined by the dimensions and the absolute viscosity 77 of the fluid inside the vestibular organ (ten Kate, 1969). As Table 1 shows, rj diverges widely in different species and measurements. These different values reveal the necessity of viscosity determination for comparative labyrinthology. According to Table 1 the...
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Taste stimuli are detected by taste receptor cells present in the oral cavity using diverse signaling pathways. Some taste stimuli are detected by G protein-coupled receptors (GPCRs) that cause calcium release from intracellular stores, whereas other stimuli depolarize taste cells to cause calcium influx through voltage-gated calcium channels (VGCCs). Although taste cells use two distinct mecha...
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Endolymph is truly unique among the extracellular body fluids, in more ways than we have previously appreciated. A number of established concepts associated with other fluids, such as the concept of “secretion” (i.e. the process of generating new fluid in volume), simply do not apply to endolymph. The high metabolic costs of endolymph generation have resulted in highly efficient homeostatic pro...
متن کاملThe mutual independence of the endolymphatic potential and the concentrations of sodium and potassium in endolymph.
The relationship between the endolymphatic potential (EP) and the sodium and potassium concentration gradients between endolymph and interstitial fluid was studied both by measuring the EP at varying concentrations of sodium and potassium in endolymph and by measuring the effect of a depressed EP on the concentrations of these cations. Ethacrynic acid was used in dogs to change the concentratio...
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The activity of the cardiac Na /Ca 2 exchanger is stimulated allosterically by Ca 2 , but estimates of the half-maximal activating concentration have varied over a wide range. In Chinese hamster ovary cells expressing the cardiac Na /Ca 2 exchanger, the time course of exchange-mediated Ca 2 influx showed a pronounced lag period followed by an acceleration of Ca 2 uptake. Lag periods were absent...
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ژورنال
عنوان ژورنال: Journal of the Association for Research in Otolaryngology
سال: 2004
ISSN: 1525-3961,1438-7573
DOI: 10.1007/s10162-003-4022-1